Lipopolysaccharide-Induced Inflammatory Genes Involved in A Quantitative Trait Loci Analysis to Map

Response: Identification of Macrophage Lipopolysaccharide-Induced Inflammatory Genes Involved in A Quantitative Trait Loci Analysis to Map

Linkage analysis of microsatellite markers on chromosome 5 in an F2 population of Japanese quail to identify quantitative trait loci affecting carcass traits

An F2 Japanese quail population was developed by crossing two strains (wild and white) to map quantitative trait loci (QTL) for performance and carcass traits. A total of 472 F2 birds were reared and slaughtered at 42 days of age. Performance and carcass traits were measured on all of the F2 individuals. Parental (P0), F1 and F2 individuals were genotyped with 3 microsatellites from quail chrom...

Macrophage inflammatory protein-2 levels are associated with changes in serum leptin concentrations following ozone-induced airway inflammation.

L ipopolysaccharide elicits a vigorous inflammatory response and has been linked to the progression of asthma and other forms of airway disease. An improved understanding of the innate immune response to lipopolysaccharide should lead to novel therapies to treat these diseases. Towards this end, we challenged 32 recombinant inbred (RI) strains of (C57BL/6J X DBA/2J) [BXD] mice with aerosolized ...

Quantitative Trait Loci Affecting Milk Production Traits on BTA 14 in Iranian Holstein Dairy Cattle: A Confirmation

The aim of this study was to refine the position of previously detected quantitative trait loci (QTL) on bovine chromosome 14 affecting milk production traits, using both linkage analysis (LA) and combined disequilibrium and linkage analysis (LDLA) methods, in Iranian Holstein dairy cattle. Analysis data was LRT (likelihood ratio test) and computed using the DMU (estimate the (co)variance compo...

Identification and prioritization genes related to Hypercholesterolemia QTLs using gene ontology and protein interaction networks

Gene identification represents the first step to a better understanding of the physiological role of the underlying protein and disease pathways, which in turn serves as a starting point for developing therapeutic interventions. Familial hypercholesterolemia is a hereditary metabolic disorder characterized by high low-density lipoprotein cholesterol levels. Hypercholesterolemia is a quantitativ...